As yet there are no independent studies on Polyhydroxy acids, and no Therapeutic
index that we are aware of. This means that we must rely on information supplied by the manufacturers of products containing
PHAs.
Polyhydroxy Acids are natural components of the skin. 'Poly - means 'multiple'.
PHAs are composed of multiple (5) water-attraction hydroxyl groups, which hydrate the skin, resulting in enhanced moisturization.
Polyhydroxy acids are very large molecules so they are less invasive and do
not penetrate into the layers of skin as readily. They are marketed for sensitive skin because they do not sting like glycolic
acid can. As glycolic acid penetrates quicker-it may sting if barrier is impaired.
One Polyhydroxy Acid contain Gluconolactone and lactobionic acid.
Gluconolactone is a PHA that is capable of cheating (binding) metals and may
also function by scavenging free radicals, thereby protecting skin from some of the damaging effects of UV radiation.
Lactobionic acid acts as a powerful antioxidant and chelates excess iron in the
skin, thereby reducing potential oxidative damage. It derives from naturally occurring lactose (milk sugar), and can be classified
as a complex PHA with potent antioxidant and humectant properties. Lactobionic acid strongly attracts and binds water to produce
a natural get matrix. Its film-forming property provides desirable softness and a smoothness to skin.
